Department of Medicinal Chemistry was established in 2015. The department has 3 professors, 7 associate professors and 2 lecturers (all of them have doctorates). Three of them are doctoral supervisor, and five of them are master supervisors. The department authorize both master degree and PhD degree in Medicinal chemistry.

Medicinal Chemistry is a discipline with a traditional focus on organic synthetic chemistry with the broad goals of drug discovery and optimization. Our faculty members are passionate in teaching and research, and zealous in training students to master the basic knowledge and experimental skills of medicinal chemistry discipline. We sincerely hope that our students become excellent pharmacy professionals with the goal of improving human health.

The Department undertakes the teaching of relevant compulsory courses (Organic Chemistry, Medicinal Chemistry, Organic Reactions for Drug Synthesis, et al) for undergraduates and elective courses (Drug Design, Artificial Intelligence in Drug Design, et al) for postgraduates.

The special research interests in the department include “development of drug candidates for treating neuropsychiatric disorders”, “development of new drugs for treating malignant tumor”, et al. Several original drug candidate molecules (ZL006, ZL006-05, ZLc-002, ZZL-7, et al), which designed and synthesized by the department, have been published in internationally renowned academic journals such as Science, Nature Medicine, Journal of Medicinal Chemistry, et al. Among them, ZL006-05 as a novel small molecule PSD-95/nNOS uncoupling agent has entered clinical trials for treating stroke and post-stroke depression. We are committed to developing innovative new medicines for the development of Healthy China and the health of the Chinese people.

Faculty

Name：Feng Feng

Research fields：1. Drug discovery and structural modification based on the active ingredients of natural products；2. Functional material design oriented to improve the druggability of natural products.

E-mail：fengfeng@njmu.edu.cn

Name：Fei Li

Research fields：Research and development of new drugs for the treatment of brain diseases

E-mail：kldlf@njmu.edu.cn

Name：Da Huo

Research fields：Nanomedicine

E-mail：huoda@njmu.edu.cn

Name：Dongyin Chen

Research fields：Studies on novel candidate drugs for treating brain diseases

E-mail：chendongyin@njmu.edu.cn

Name: Nan Jiang

Research fields: Computer- and Artificial Intelligence-aided Drug Design

E-mail: jiangnan@njmu.edu.cn

Name：Yajuan Qin

Research fields：1. Development of protein-protein interaction uncoupling agents for the treatment of depression and stroke; 2. Diagnosis and chemical regulation of neurodegenerative diseases;

E-mail：yjqin@njmu.edu.cn

Name：Dongsheng Zhu

Research fields：Structure-based drug discovery, Target identification using chemical proteomics

E-mail: zhuds@njmu.edu.cn

Name：Hongjuan Zhang

Research fields：1. Chemoenzymatic synthesis of key chiral pharmaceutical intermediates. 2. Construction of a new high-performance biocatalytic system to apply it in efficient separation and preparation of natural products, chiral drugs.

E-mail：zhanghj@njmu.edu.cn

Name：Weilin Chen

Research fields：Small molecule innovative drug development for oncology and neuropsychiatric diseases

E-mail: chenweilin@njmu.edu.cn

Name：Bin Wu

Research fields：anti-ischemic stroke agents

E-mail：wubin@njmu.edu.cn

Name：Wang Xiuzhen

Research fields：Design of antitumor drugs and drug delivery systems

E-mail:xiuzhenwang@njmu.edu.cn

Name: Yifan Fu

Research fields：Discovery of active natural new products

E-mail: yifanfu@njmu.edu.cn