马腾飞，教授，博士生导师。南京医科大学药物依赖及戒断转化医学研究中心主任，现代毒理学教育部重点实验室PI，江苏特聘教授，江苏省防范毒品滥用专家组成员。长期从事神经药理学研究，近年来发表SCI学术论文50余篇，收录在Nature Neuroscience, Journal of Clinical Investigation (JCI), Biological Psychiatry等国际期刊。主持国家自然科学基金面上项目，承担江苏省“双创团队”，司法部司法行政戒毒优势教育戒治等项目，主持省级教育研究课题、省级一流课程、参编省级“十四五”规划教材，获得市厅级科技进步奖二项。目前担任中国毒理学会药物依赖性专委会委员、中国药物滥用防治协会成瘾与脑科学分会委员、中国药理学会神经精神药理学专委会委员、中国生理学会中医与脑稳态专委会委员、江苏省老年医学学会麻醉学分会常务委员。Neuropharmacology and Therapy期刊编委。
招生：招收药理学、药学专业硕士和药理学专业博士研究生；常年招收博士后；
联系方式：tfma@njmu.edu.cn
实验室主要技术条件：
1.膜片钳技术：全细胞记录，细胞贴附式记录等
2.在体电生理学技术：在体电生理结合动物自由活动行为学
3.在体与离体光遗传学技术：光调控行为与离体验证
4.在体与离体钙影像学技术：结合行为的钙信号记录
5.单突触神经元示踪技术：神经环路机制探索
6. 3D重建细胞内示踪技术：神经元树突棘分析
7.免疫荧光、免疫印迹、行为学等
代表性论著：
1. Li J, Zhou Y, Yin F, Du Y, Xu J, Fan S, Li Z, Wang X, Shen Q, Zhu Y, Ma T*. The Orbitofrontal Cortex to Striatal Cholinergic Interneuron Circuit Controls Cognitive Flexibility Shaping Alcohol-Seeking Behavior. Biol Psychiatry. 2025 Mar 15;97(6):614-626.
2. Fan S, Qi Y, Zhang F, Shi Y, Ma K, Pan Q, Jiang A, He L, Zhang J, Ma T*, Zhou L*. Dissecting the neuronal mechanisms of pinoresinol against methamphetamine addiction based on network and experimental pharmacology. Phytomedicine. 2025 Jan: 136:156322.
3. Qi Y, Zhou Y, Li J, Zhu F, Guo G, Wang C, Yu M, Wang Y, Ma T*, Feng S, Zhou L. 3'-Deoxyadenosin alleviates methamphetamine-induced aberrant synaptic plasticity and seeking behavior by inhibiting the NLRP3 inflammasome. Neural Regen Res. 2024 Oct 1;19(10):2270-2280.
4. Li Z, Li J, Wei Y, Zou W, Vidjro O, Wang J, Zhou L, Zhu Y*, Ma T*. Anterior and Posterior Basolateral Amygdala Projections of Cell Type-Specific D1-Expressing Neurons From the Medial Prefrontal Cortex Differentially Control Alcohol-Seeking Behavior. Biol Psychiatry. 2024 May 15;95(10):963-973.
5. Gao K, Hu M, Li J, Li Z, Xu W, Qian Z, Gao F*, Ma T*. Drug-detecting bioelectronic nose based on odor cue memory combined with a brain computer interface. Biosens Bioelectron. 2024 Jan 15:244:115797.
6. Zhu Y, Wang K, Ma T#, Ji Y, Lou Y, Fu X, Lu Y, Liu Y, Dang W, Zhang Q, Yin F, Wang K, Yu B, Zhang H, Lai J, Wang Y. Nucleus accumbens D1/D2 circuits control opioid withdrawal symptoms in mice. J Clin Invest. 2023 Sep 15;133(18):e163266.
7.Wang X, Hu M, Xie Q, Geng C, Jin C, Ren W, Fan J, Ma T*, Hu B**. Amyloid β oligomers disrupt piriform cortical output via a serotonergic pathway. Neurobiol Aging. 2023; 121:64-77.
8. Li Z, Vidjro O, Guo G, Du Y, Zhou Y, Xie Q, Li J, Gao K, Zhou L*, Ma T*. NLRP3 deficiency decreases alcohol intake controlling anxiety-like behavior via modification of glutamatergic transmission in corticostriatal circuits. J Neuroinflammation. 2022; 19(1):308.
9. Ma T, Huang Z, Xie X, Cheng Y, Zhuang X, Childs M, Gangal H, Smith L, Simth L, Zhou Y, Wang J. Chronic alcohol drinking persistently suppresses thalamostriatal excitation of cholinergic neurons to impair cognitive flexibility. J Clin Invest. 2022. 2022; 132(4):e154969.
10. Huang J, Zhang F, Su M, Li J, Yi W, Hou L, Yang S, Liu J, Zhang H, Ma T*, Wu D*. MeCP2 prevents age-associated cognitive decline via restoring synaptic plasticity in a senescence-accelerated mouse model. Aging Cell. 2021; 20(9):e13451.
11.Gao K, Gao F, Li J, He C, Liu M, Zhu Q, Qian Z, Ma T*, Wang P*. Biomimetic integrated olfactory sensory and olfactory bulb systems in vitro based on a chip. Biosens Bioelectron. 2021; 171:112739.
12. Ma T, Cheng Y, Roltsch Hellard E, Wang X, Lu J, Gao X, Huang C.C.Y. Wei XY, Ji JY, Wang J. Bidirectional and long-lasting control of alcohol seeking behavior by corticostriatal LTP and LTD. Nature Neuroscience, 2018; 21(3):373-383.
13. Ma T, Barbee B, Wang X, Wang J. Alcohol Induces Input-Specific Aberrant Synaptic Plasticity in the Rat Dorsomedial Striatum. Neuropharmacology. 2017; 123:46-54.
14. Cheng Y#, Huang CCY#, Ma T#, Wei X, Wang X, Lu J, Wang J. Distinct Synaptic Strengthening of the Striatal Direct and Indirect Pathways Drives Alcohol Consumption. Biol Psychiatry. 2017; 81(11):918-929.
15. Wei X#, Ma T#, Cheng Y, Huang CCY, Wang X, Lu J, Wang J. Dopamine D1 or D2 receptor-expressing neurons in the central nervous system. Addict Biol. 2018; 23(2):569-584.
