方丹君,南京医科大学药学院副教授。
教育经历:
2004/8 - 2010/1,Case western reserve university,化学,博士
2001/9 - 2004/6,浙江大学,化学,硕士
1997/9 - 2001/6,浙江工业大学,工业分析,学士
工作经历:
2010/5 – 2010/10 Case western reserve university,化学,博士后
2011/11 - 至今,南京医科大学,药学院,副教授
主持或参加科研项目及人才计划项目情况:
1、主持国家自然科学基金面上项目一项,高通量单细胞分析平台研究细胞表面胆固醇与脂分子的相互作用,科研进行中。
2、主持国家自然科学基金青年项目一项,快速单细胞胆固醇电分析平台的建立及其在斯达汀类药物开发中的应用,已结题。
3、留学回国科技活动项目择优资助经费。
代表性研究成果:
1、 Wang, Rui; Fang, Danjun*. Detection of Phosphatidylserine in Plasma Membrane at Single Apoptotic Cells using Electrochemiluminescence. RSC Advances, 2017, 7, 12969 - 12972.
2、 Zuo, Huanzhen; Wang, Rui; Jiang, Dechen; Fang, Danjun*. Determining the Composition of Active Cholesterol in the Plasma Membrane of Single Cells by using Electrochemiluminescence. ChemElectroChem, ASAP
3、 Zhou, Junyu; Ma, Guangzhong; Chen, Yun; Fang, Danjun*; Jiang, Dechen*; Chen, Hong-yuan. Electrochemiluminescence Imaging for Parallel Single-Cell Analysis of Active Membrane Cholesterol. Analytical Chemistry, 2015, 87 (16): 8138-8143.
4、 Zhuang, Lihong; Zuo, Huanzhen; Wu, Zengqiang; Wang, Yu; Fang, Danjun*; Jiang, Dechen*. Enhanced electrochemical nanoring electrode for analysis of cytosol in single cells. Analytical Chemistry, 2014, 86 (23): 11517-11522.
5、 Han, Fangfei; Jiang, Hui; Fang, Danjun*; Jiang, Dechen*. Potential-resolved electrochemiluminescence for determination of two antigens at the cell surface. Analytical Chemistry, 2014, 86 (14): 6896-6902.
6、 Tian, Chunxiu; Zhou, Junyu; Wu, Zeng-Qiang; Fang, Danjun*; Jiang, Dechen*. Fast Serial Analysis of Active Cholesterol at the Plasma Membrane in Single Cells. Analytical Chemistry, 2013, 86 (1): 678-684.
7、 Ma, Guangzhong; Zhou, Junyu; Tian, Chunxiu; Jiang, Dechen*; Fang, Danjun*; Chen, Hongyuan. Luminol electrochemiluminescence for the analysis of active cholesterol at the plasma membrane in single mammalian cells. Analytical Chemistry, 2013, 85 (8): 3912-3917.
8、 Fang, Danjun; West, Richard H.; Manson, Mary E.; Ruddy, Jennifer; Jiang, Dechen; Previs, Stephen F.; Sonawane, Nitin D.; Burgess, James D.; Kelley, Thomas J.* Increased plasma membrane cholesterol in cystic fibrosis cells correlates with CFTR genotype and depends on de novo cholesterol synthesis. Respiratory Research, 2010, 11:61.
9、 Fang, Danjun; Jiang, Dechen; Lu,Hui; Chiel,Hillel J.; Kelley,Thomas J.; Burgess James D*. Observation of Cellular Cholesterol Efflux at Microcavity Electrodes. J. Am. Chem. Soc., 2009, 131 (34): 12038–12039.
10、 Jiang, Dechen; Fang, Danjun; Kelley, Thomas J.; Burgess, James. D.* Electrochemical Analysis of Cell Plasma Membrane Cholesterol at the Airway Surface of Mouse Trachea. Analytical Chemistry, 2008, 80 (4): 1235–1239.
11、 方丹君,江德臣,周俊宇,一种电致化学发光成像装置及其应用,中国,201410126893.4。 专利
12、 方丹君,江德臣,姜晖,韩芳霏,一种基于鲁米诺和联吡啶钌的电位分辨电致化学发光检测方法及其应用,中国,201410104233.6。 专利
13、 方丹君,江德臣,田春秀,马光中,一种微电极阵列及其在检测单细胞表面活化胆固醇上的应用,中国,201310654110 .5。 专利