胡琴,女,南京医科大学教授,博士生导师,药学院副院长。教学方面获学校教学名师、“扬子江奖教金”优秀奖等奖项,科研方面获校级“十一五”、“十二五”期间科技先进工作者光荣称号。学术兼职:国家自然科学基金网评专家;中华医学会医学化学分会副理事长;江苏省科委科技项目、成果评审专家组成员;江苏省食品药品监督管理局新药审评委员;江苏省化学化工学会分析化学分会理事。
在教学的同时,主要从事半导体量子点和碳点纳米荧光材料、人工智能纳米材料的合成及其应用于生命系统中微量物质的分析等研究。主持多项省级、国家级科研课题。在国内外主要期刊发表研究论文80余篇。以第一作者身份获授权国家发明专利6件,主编教材和专著7部。
目前研究方向
1、半导体量子点、碳点纳米荧光材料的合成及其作为荧光探针在药物分析中的应用。
2、金属-有机骨架材料的合成及其在样品预处理及分析中的应用。
3、分子印迹纳米材料的研制及其在样品预处理中的应用。
近期发表的SCI论文
1.Yueyue Song, Tang Tang, Xu Wang, Guanhong Xu, Fangdi Wei, Yanzi Wu, Quan Song,Yujie Ma, Yunsu Ma, Yao Cen, Qin Hu*, Highly selective and sensitive detection of adenosine utilizing signalamplification based on silver ions-assisted cation exchange reactionwith CdTe quantum dots, Sensor. Actuat. B-Chem., 2017, 247, 305-311
2. Yanzi Wu, Guanhong Xu, Fangdi Wei, Quan Song, Tang Tang, Xu Wang, Qin Hu*, Determination of Hg (Ⅱ) in tea and mushroom samples based on metal-organic frameworks as a solid phase extraction sorbent, Microporous & Mesoporous Materials, 2016, 235, 204-210
3. Ling Zhu, Guanhong Xu, Quan Song, Tang Tang, Xu Wang, Fangdi Wei, Qin Hu*, Highly sensitive determination of dopamine by a turn-on fluorescent biosensor based on aptamer labeled carbon dots and nano-graphite, Sensor. Actuat. B-Chem., 2016, 231, 506-512
4. Fangdi Wei, Guanhong Xu, Yanzi Wu, Xu Wang, Jing Yang, Liping Liu, Pin Zhou, Qin Hu*, Molecularly imprinted polymers on dual-color quantum dots for simultaneous detection of norepinephrine and epinephrine, Sensor. Actuat. B-Chem., 2016, 229, 38-46
5. Jinna Wang, Guanhong Xu, Fangdi Wei, Jing Yang, Ping Zhou, Qin Hu*, A novel Fe3O4/CdTe fluorescence probe for sialic acid detection based on phenylboronic acid- sialic acid recognition system, RSC Advances, 2016, 6, 481-488
6. Yan Lin, Guanhong Xu, Fangdi Wei, Aixia Zhang, Jing Yang, Qin Hu*, Detection of CEA in human serum using surface-enhanced Raman spectroscopy coupled with antibody-modified Au and γ-Fe2O3@Au nanoparticles, Journal of Pharmaceutical and Biomedical Analysis, 2016, 121, 135-140
7. Wei Liu, Aixia Zhang, Guanhong Xu, Fangdi Wei, Jing Yang, Qin Hu*, Manganese modified CdTe/CdS quantum dots as an immunoassay biosensor for the detection of Golgi protein-73, Journal of Pharmaceutical and Biomedical Analysis, 2016, 117, 18-25
8. Yanzi Wu, Guanhong Xu, Wei Liu, Jing Yang, Fangdi Wei, Lei Li, Wen Zhang, Qin Hu*, Postsynthetic modification of copper terephthalate metal-organic frameworks and their new application in preparation of samples containing heavy metal ions, Microporous & Mesoporous Materials, 2015, 210, 110-115
9. Ling Zhu, Guanhong Xu, Fangdi Wei, Jing Yang, Qin Hu*, Determination of melamine in powdered milk by molecularly imprinted stir bar sorptive extraction coupled with HPLC, Journal of Colloid and Interface Science, 2015, 454, 8-13
10. Fangdi Wei, Yanzi Wu, Guanhong Xu, Yankun Gao, Jing Yang, Liping Liu, Ping Zhou, Qin Hu*, Molecularly imprinted polymer based on CdTe@SiO2 quantum dots as a fluorescent sensor for the recognition of norepinephrine, Analyst, 2014, 139, 5785-5792
代表性发明专利
1. CdTe/CdS/ZnS/SiO2量子点的制备方法
专利号:ZL 201410046859.6 授权公告日:2015.08.19
发明人:胡琴, 魏芳弟,刘丽云,许贯虹,杨静,周萍,刘利萍
2. 碲化镉量子点表面对氨基酚印迹聚合物及其制备方法和应用
专利号:ZL 201310456073.7 授权公告日:2015.10.19
发明人:胡琴,路霞林,魏芳弟,许贯虹,刘利萍,周萍,杨静
3. 双酚A伪模板分子印迹搅拌棒及其制备方法
专利号:ZL 201110200548.7 授权公告日:20130612
胡琴,盛娜,魏芳弟,许贯虹,蔡政,都述虎,李飞,周学敏
4. 一种酚类纳米硅胶表面分子印迹材料的制备方法
专利号:200910029992.X 授权公告日:2010.11.03
胡琴,朱荣,赵文慧,魏芳弟,蔡政,李飞
主编的代表性教材及专著
1. 基础化学实验(双语教材,第二版),胡琴、祁嘉义主编,高等教育出版社,2017年3月。
2. 分析化学(案例版,第二版)胡琴、彭金咏主编,科学出版社,2016年6月。
3. 基础化学(第三版),胡琴、祁嘉义主编,高等教育出版社,2014年8月。
4. 医学检验辞典, 胡琴主编,化学工业出版社,2008年9月。