陈立娜

发布时间:2017-04-21浏览次数:2049


陈立娜,教授,研究生导师。国家自然科学基金网评专家,获江苏中医药科学技术奖二等奖(排名第二),江苏省高校青蓝工程优秀青年骨干教师培养人选,南京医科大学优秀中青年学科(学术)带头人、 十二五科技工作先进个人、优秀研究生导师团队成员。先后主持国家自然科学基金项目3项,中国博士后科学基金1项,江苏省教育厅自然科学基金2项,南医大-苏盐智慧健康科技创新研发资金项目1项,校级课题5项。作为主要参加人员参与国家863计划项目1项,国家自然科学基金项目3项。国内外主要期刊发表研究论文40余篇。以第一作者身份获授权国家发明专利4件,主编或参编十二五 “十三五教材6部。

    目前研究方向:现代分析技术在天然药物活性成分研究中的应用;天然药物活性成分及其质量评价研究。

    近期发表的SCI论文

  1. Jiaojiao Huang, Chenghong Sun,Dandan Yao, Chong-Zhi Wang,Lei Zhang,Yu Zhang, Lina Chen*,Chun-Su Yuan. Novel surface imprinted magnetic mesoporous silica as artificial antibodies for efficient discovery and capture of candidate nNOS–PSD-95 uncouplers for stroke treatment, Journal of Materials Chemistry B, 2018, 6, 1531-1542.

  2. Dandan Yao , Lei Zhang , Jiaojiao Huang , Chenghong Sun , Yu Zhang , Xiaoli Gu , Chong-Zhi Wang , Fei Li , Lina Chen *, Chun-Su Yuan. A surface magnetic imprinted polymers as artificial receptors for selective and efficient capturing of new neuronal nitric oxidesynthase–post synaptic density protein-95 uncouplers,Journal of Pharmaceutical and Biomedical Analysis ,2018,154:180–190.

3. Xiaoli Gu,Jiaojiao Huang,Lei Zhang,Yu zhang, Chong-Zhi Wang, Chenghong Sun, Dandan Yao,Fei Li, Lina Chen* ,Chun-Su Yuan. Efficient discovery and capture of new neuronal nitric oxide synthase-postsynaptic density protein-95 uncouplers from herbal medicines using magnetic molecularly imprinted polymers as artificial antibodies. Journal of Separation Science,2017,40(17):3522-3534.

4. Chenghong Sun, Jinhua Wang, Jiaojiao Huang, Dandan Yao, Chong-Zhi Wang, Lei Zhang, Shuying Hou*, Lina Chen* ,Chun-Su Yuan. The multi-template molecularly imprinted polymer based on SBA-15 for selective separation and determination of Panax notoginseng Saponins simultaneously in biological samples.Polymers,2017,9(12):653.

5. Hongliang He, Xiaoli Gu, Liying Shi, Junli Hong, Hongjuan Zhang, Yankun

Gao, Shuhu Du, Lina Chen*. Molecularly imprinted polymers based on SBA-15

for selective solid-phase extraction of baicalein from plasma samples. Analytical

and Bioanalytical Chemistry, 2015,407(2):509–519.

6. Hongliang He, Hong Li, Yankun Gao, Dong Chen, Liying Shi, Jin Peng, Shuhu Du, Lina Chen*. A novel molecularly imprinted polymer for the solid-phase extraction of Tanshinones from serum,Analytical Letters, 2015, 48:47-60.

7. Shuying Hou, Songling Yang, Hongliang He, Yan Chen, Jinhua Wang, Yang Wang*, Lina Chen*. Multi-templates molecularly imprinted polymer for the specific solid-phase extraction of saponins from Panax notoginseng herbal extract. Current Pharmaceutical Analysis, 2015,11(3):292-299.

8. Xiaoli Gu, Hongliang He, Chong-zhi Wang, Yankun Gao, Hongjuan Zhang, Junli Hong,ShuhuDu,LinaChen*,Chun-suYuan.Synthesis of surface nano-molecularly imprinted polymers for sensitive baicalin detection from biological samples. RSC Advances, 2015, 5, 41377–41384.

9. Hong Li, Hongliang He, Jiaojiao Huang,Chong-Zhi Wang, Xiaoli Gu, Yankun Gao, Hongjuan Zhang, Shuhu Du, Lina Chen*, Chun-Su Yuan.A novel molecularly imprinted method with computational simulation for the affinity isolation and knockout of baicalein from Scutellaria baicalensis.Biomedical Chromatography, 2016,30(2):117-125.

10. Xianjun Jia, Hong Li, Jing Luo, Qing Lu,Yan Peng, Shuhu Du, Guijun Zhang, Lina Chen*. Rational design of core-shell molecularly imprinted polymer based on computational simulation and Doehlert experimental optimization: application to theseparationof tanshinone IIA from Salvia Miltiorrhiza Bunge. Analytical and Bioanalytical Chemistry, 2012,403(9):26912703.

代表性发明专利

1.丹参酮类化合物芯-壳结构复合纳米表面分子印记聚合物的制备方法

专利号:ZL201010167614.0授权日:2011.09.21

申请人:陈立娜 都述虎 贾宪军 刘利萍

2. 黄芩素分子印迹聚合物及其制备方法和应用

专利号:ZL201310408025.0授权日:2016.04.27

申请人:陈立娜,李虹,何宏亮,高艳坤,史丽英,都述虎

3. 多模板单分散三七活性皂苷分子印迹聚合物及其制备方法

专利号:ZL201310495697.X授权日:2016.01.06

申请人:陈立娜,何宏亮,高艳坤

4. 介孔分子筛SBA-15复合纳米表面印迹聚合物及其制备方法

专利号:ZL201310496400.1授权日:2016.01.20

申请人:陈立娜,何宏亮,史丽英,程清清,高艳坤,都述虎


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