胡晔晨，博士，南京医科大学药学院副教授，江苏省“双创博士”。主持多项科研项目，发表多篇学术论文，获多篇专利授权。现任江苏省化学化工学会第十三届理事会色谱及分离科学专业委员会委员。
主讲课程：《医用化学》、《基础化学B》、《化妆品中的化学》、《吃货必懂的食品化学与营养健康》、《化学之眼探寻医药奥秘》、《药学进展》等。获江苏省微课比赛三等奖、江苏省“领航杯”教师素养提升活动特等奖、南京医科大学教师创新大赛一等奖等。
研究方向：
（1）蛋白质组学样品预处理新技术开发
（2） 基于质谱的生物大分子高灵敏定量分析方法开发
联系方式：
E-mail：huyechen@njmu.edu.cn
主持科研项目：
（1）国家自然科学基金青年基金项目（22104061）
（2）江苏省高等学校自然科学研究项目-面上项目（25KJB150022）
（3）加拿大多伦多大学精准医学PRiME计划资助对象（2021-2022）
代表性论文：
（1）Yechen Hu#, Bo Jiang#, Yejing Weng, Zhigang Sui, Baofeng Zhao, Yuanbo Chen, Lukuan Liu, Qiong Wu, Zhen Liang, Lihua Zhang*, and Yukui Zhang. Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome. Nat Commun 2020, 11, 6226.
（2）Yechen Hu#, Zhongcheng Wang, Liang Liu, Jianhua Zhu, Dongxue Zhang, Mengying Xu, Yuanyuan Zhang, Feifei Xu and Yun Chen*. Mass spectrometry-based chemical mapping and profiling toward molecular understanding of diseases in precision medicine. Chem Sci 2021, 12, 7993.
（3）Yechen Hu*, Xiao Cao, Jingjing Zhao, Haoran Chen, Chuhao Cheng, Feifei Xu, and Yun Chen*. Dual-affinity HZIF-1Mo microcolumn platform for quantitative profiling of N‑phosphorylation in breast cancer subtypes. Anal Chem 2026, 98, 11, 8321–8330.
（4）Leheng Wang#, Jiyao Zhou#, Zimeng Chen, Yi Lu, Guang Huang, Yechen Hu*, Changgao Huang, Bangbang Wei and Yun Chen*. Hierarchical magnetic core-shell nanoreactor (Fe3O4@SA/Trypsin@UiO-66) for efficient sensing of protease inhibitors in food and feed products. Anal Chim Acta 2026, 1416, 345770.
（5）Xiuyu Chen, Jianhua Zhu, Bo Sun, Xian Zhang, Yechen Hu* and Yun Chen*. A mass-tagged MOF nanoprobe approach for ultra-sensitive protein quantification in tumor-educated platelets. Chem Comm 2022, 58, 7160.
（6）Yechen Hu, Bo Jiang*. Selective enrichment tandem β-elimination assisted strategy for n-phosphorylation analysis. Talanta 2022, 247, 123580.
（7）Yechen Hu#, Bo Jiang#, Jianhui Liu, He Wang, Zhigang Sui, Baofeng Zhao, Zhen Liang, Lihua Zhang* and Yukui Zhang. Zn(II)-DPA functionalized graphene oxide two-dimensional nanocomposites for N-phosphoproteins enrichment. Talanta 2022, 243, 123384.
（8）Yechen Hu#, Hao Jiang#, Baofeng Zhao*, Kaiguang Yang, Zhen Liang, Lihua Zhang* and Yukui Zhang. Quantitative proteomics of epigenetic histone modifications in MCF-7 cells under estradiol stimulation. Anal Methods 2021, 13(4), 469-476.
（9）Jiaxi Peng#, Yechen Hu#, Hongyan Zhang, Lihong Wan, Li Wang, Zhen Liang, Lihua Zhang* and Ren’an Wu*. High anti-interfering profiling of endogenous glycopeptides for human plasma by the dual-hydrophilic metal-organic framework. Anal Chem 2019, 91, 7, 4852-4859.
（10）Yechen Hu, Yang Li, Hang Gao, Bo Jiang, Xiaodan Zhang, Xiao Li, Qiong Wu, Zhen Liang, Lihua Zhang and Yukui Zhang. Cleavable hydrophobic derivatization strategy for enrichment and identification of phosphorylated lysine peptides. Anal Bioanal Chem 2019, 411, 4159-4166.
（11）Yechen Hu#, Yejing Weng#, Bo Jiang, Xiao Li, Xiaodan Zhang, Baofeng Zhao, Qiong Wu, Zhen Liang, Lihua Zhang* and Yukui Zhang. Isolation and identification of phosphorylated lysine peptides by retention time difference combining dimethyl labeling strategy. Sci China Chem 2019, 62, 708-712.
