赵爽，博士，副教授。2020年博士毕业于南京医科大学药学院药理学专业。主要从事心血管疾病的分子机制和靶向干预研究，包括心肌肥厚、主动脉夹层、糖尿病血管并发症、动脉粥样硬化等，相关成果发表于国际知名期刊Circulation、Hepatology、Redox Biology、Acta Pharmacol Sin等杂志。主持国家自然科学基金青年基金项目、中国科协青年人才托举工程、中国博士后科学基金等多项科研项目。获江苏省科学技术奖一等奖及中华医学科技奖二等奖，授权国家发明专利4件。
联系方式：zhaoshuang@njmu.edu.cn
教育与工作经历：
2011.09-2015.07 南京医科大学 基础医学院 生物技术（本科）
2015.09-2017.07 南京医科大学 基础医学院病理生理学（硕士研究生）
2017.09-2020.07 南京医科大学 药学院 药理学（博士研究生）
2020.07-2022.07 南京医科大学 药学院 心脑血管药物重点实验室（博士后）
2022.09-至今 南京医科大学 药学院 副教授
代表性论文：
1. Shuang Zhao#; Xin Tang#; Zian Miao; Yurong Chen; Jiawei Cao; Tianyu Song; Daiting You; Yanqing Zhong; Zhe Lin; Dan Wang; Zhiguang Shi; Xinlong Tang; Dongjin Wang; Shaoliang Chen; Liansheng Wang; Aihua Gu; Feng Chen; Liping Xie; Zhengrong Huang*; Hong Wang*; Yong Ji*; Hsp90 S-nitrosylation at Cys521, as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis, Redox Biol. 2022;52:102290.
2. Shuang Zhao#; Tianyu Song#; Ziyu Wang; Jie Gao; Jiawei Cao; Lulu Hu; Zhengrong Huang*; Liping Xie*; Yong Ji*; S-nitrosylation of Hsp90 promotes cardiac hypertrophy in mice through GSK3β signaling, Acta Pharmacol Sin. 2022;43(8):1979-1988.
3. Shuang Zhao; Tianyu Song; Yue Gu; Yihua Zhang; Siyi Cao; Qing Miao; Xiyue Zhang; Hongshan Chen; Yuanqing Gao; Lei Zhang; Yi Han; Hong Wang; Jun Pu; Liping Xie*; Yong Ji*; Hydrogen Sulfide Alleviates Liver Injury Through the S-Sulfhydrated-Kelch-Like ECH-Associated Protein 1/Nuclear Erythroid 2-Related Factor 2/Low-Density Lipoprotein Receptor-Related Protein 1 Pathway, Hepatology. 2021;73(1): 282-302.
4. Shanshan Luo#; Chuiyu Kong#; Shuang Zhao#; Xin Tang#; Yu Wang; Xuechun Zhou; Rui Li; Xingeng Liu; Xinlong Tang; Shixiu Sun; Wei Xie; Zhi-Ren Zhang; Qing Jing; Aihua Gu; Feng Chen; Dongjin Wang; Hong Wang*; Yi Han*; Liping Xie*; Yong Ji*; Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration, Circulation. 2023;147(18):1382-1403.
5. Xin Tang; Lihong Pan; Shuang Zhao; Feiyue Dai; Menglin Chao; Hong Jiang; Xuesong Li; Zhe Lin; Zhengrong Huang; Guoliang Meng; Chun Wang; Chan Chen; Jin Liu; Xin Wang; Albert Ferro; Hong Wang; Hongshan Chen; Yuanqing Gao; Qiulun Lu; Liping Xie*; Yi Han*; Yong Ji*; SNO-MLP (S-Nitrosylation of Muscle LIM Protein) Facilitates Myocardial Hypertrophy Through TLR3 (Toll-Like Receptor 3)-Mediated RIP3 (Receptor-Interacting Protein Kinase 3) and NLRP3 (NOD-Like Receptor Pyrin Domain Containing 3) Inflammasome Activation, Circulation. 2020;141(12): 984-1000.
6. Liping Xie#; Yue Gu#; Mingliang Wen; Shuang Zhao; Wan Wang; Yan Ma; Guoliang Meng; Yi Han; Yuhui Wang; George Liu; Philip K Moore; Xin Wang; Hong Wang; Zhiren Zhang; Ying Yu; Albert Ferro; Zhengrong Huang*; Yong Ji*; Hydrogen Sulfide Induces Keap1 S-sulfhydration and Suppresses Diabetes-Accelerated Atherosclerosis via Nrf2 Activation, Diabetes. 2016;65(10): 3171-3184.
