张丽颖，博士，南京医科大学副教授，江苏省“青蓝工程”高层次人才。主要从事现代光谱新技术的应用研究。发表SCI论文50余篇，主持/参与国家自然科学基金7项，申请专利2项。
主持/参与科研项目：
1. 国家自然科学基金，61605084，拉曼响应的分子印记单层传感器对潜在肿瘤标志物金属硫蛋白的特异性识别和快速检测，2017-01至2019-12，21万元，已结题，主持；
2. 江苏省高校自然科学研究，16KJB150029，发展用于肿瘤潜在标志物金属硫蛋白特异性快速检测方法，2016-09至2018-06，3万元，已结题，主持；
3. 国家自然科学基金，22274080，声流控操纵DNA编码荧光探针分级聚集应用于多肿瘤标志物同步可视化检测，2023-01-01至2026-12-31，54万，在研，参加；
4. 国家自然科学基金，21775073，Ehrlich反应诱导表面增强共振拉曼散射及其在吲哚类植物生长素选择性检测中的应用，2018-01至2021-12，65万元，已结题，参加；
5. 国家自然科学基金，21275075，SERS活性的芯-壳型分子印记传感器对青霉素类药物中过敏原的快速检测，2013-01至2016-12，78万元，已结题，参加；
6. 国家自然科学基金，81773986，肠道菌群介导的人参皂苷改善动脉粥样硬化的作用和机制研究，2017-08至2021-12，55万元，已结题，参加；
7. 国家自然科学基金，21605086，基于多道DNA-Peptide探针/准定向蛋白质组学法的microRNA定量方法研究，2016-08至2019-12，20万元，已结题，参加。
代表性科研论文
1) P Chen, Y Peng, L Lin, Y Yuan, J Chen, J Mo, J Miao, H He, Y Jin*, L Zhang*, S Du*, Au/CeO2 NR restricted inside Cu-MOFs: a three-in-one artificial enzyme with synergistically enhanced peroxidase-like activity for dual-mode sensing of multiple biomarkers, ACS Sustainable Chem. Eng. 2023, 11, 8106.
2) P Chen, J Wu, H Fei, H He, S Cao, L Zou, Y Jin, L Zhang*, S Du*, Acoustofluidics-manipulated triple-emission fluorescent nanoprobe aggregates with multicolor-variation for colorimetric quantitative assay, Chem. Eng. J. 2022, 441, 135976.
3) J Wu, P Chen, J Chen, X Ye, S Cao, C Sun, Y Jin, L Zhang*, S Du*, Integrated ratiometric fluorescence probe-based acoustofluidic platform for visual detection of anthrax biomarker, Biosens. Bioelectron. 2022, 214, 114538.
4) T Lu, L Wang, Y Xia, Y Jin, L Zhang*, S Du*, A multimer-based SERS aptasensor for highly sensitive and homogeneous assay of carcinoembryonic antigens, Analyst 2021, 146, 3016.
5) Y Xia, T Lu, L Wang, J Mo, Y Jin, L Zhang*, S Du*, Intrinsic Raman signal amplification for rapid identification and detection of methylglyoxal in manuka honey, Anal. Chim. Acta 2021, 1181, 338902.
6) L Wang, J Mo, Y Xia, T Lu, Y Jin, Y Peng, L Zhang*, Y Tang*, S Du*, Monitoring allergic reaction to penicillin based on ultrasensitive detection of penicilloyl protein using alkyne response SERS immunosensor, J. Pharm. Biomed. Anal. 2021, 206, 114377.
7) L Zhang, Z Tian, H Bachman, P Zhang, TJ Huang*, A cell-phone-based acoustofluidic platform for quantitative point-of-care testing, ACS Nano 2020, 14, 3159.
8) Y Cai, J You, Z You, F Dong, S Du*, L Zhang*, Profuse color-evolution-based fluorescent test paper sensor for rapid and visual monitoring of endogenous Cu2+ in human urine, Biosens. Bioelectron. 2018, 99, 332.
9) Q Da, Y Gu, X Peng, L Zhang*, S Du*, Colorimetric and visual detection of mercury(II) based on the suppression of the interaction of dithiothreitol with agar-stabilized silver-coated gold nanoparticles, Microchim. Acta 2018, 185, 357.
10) L Zhang1, Y Jin1, X Huang, Y Zhou, S Du*, Z Zhang, Ligand replacement approach to Raman-responded molecularly imprinted monolayer for rapid determination of penicilloic acid in penicillin, Anal. Chem. 2015, 87, 11763.
11) L Zhang, Y Jin, H Mao, L Zheng, J Zhao, Y Peng, S Du*, Z Zhang, Structure-selective hot-spot Raman enhancement for direct identification and detection of trace penicilloic acid allergen in penicillin, Biosens. Bioelectron. 2014, 58, 165.
论著之外的代表性研究成果和学术奖励:
1. 张丽颖，陈攀攀，都述虎，金阳，袁遥遥，陈洁，莫锦灵，苗嘉艺；一种类过氧化物酶Au/CeO2 NR@Cu-MOFs及制备方法和应用，CN116116463A
2. 都述虎，蔡月青，尤军辉，张丽颖；一种用于可视化检测铜离子的荧光宽色度试纸及其制备方法和应用，ZL 201710556279.5
