唐欣，副教授、硕士生导师。
2013年-2016年，获得南京医科大学，病理学与病理生理学，硕士学位；
2016年-2019年，获得南京医科大学，病理学与病理生理学，博士学位；
2019年2020年，江苏省心脑血管药物重点实验室，讲师；
2020年至今，江苏省心脑血管药物重点实验室，副教授。
主持了包括国家自然科学基金面上项目、青年项目等4项国家级省级基金。在Circulation、Circ Res、Redox Biol等学术期刊上发表论文16篇。获江苏省科学技术奖一等奖一项（2021）、中华医学科技奖二等奖一项（2019）。授权国家发明专利2件。Email: njmutangxin@njmu.edu.cn
研究方向：心血管疾病的分子机制及药物防治研究。
研究内容包括：
1.心脏重构、主动脉夹层、动脉粥样硬化、糖尿病血管损伤等心血管疾病的病理生理分子机制及药物的防治；
2.生活活性小分子NO、H2S等介导的蛋白质巯基修饰在心血管疾病中的作用及机制研究。
近年发表论文：
1.Xin Tang#, Lihong Pan, Shuang Zhao, Feiyue Dai, Menglin Chao, Hong Jiang, Xuesong Li, Zhe Lin, Zhengrong Huang, Guoliang Meng, Chun Wang, Chan Chen, Jin Liu, Xin Wang, Albert Ferro, Hong Wang, Hongshan Chen, Yuanqing Gao, Qiulun Lu, Liping Xie*, Yi Han*, Yong Ji* (2020). SNO-MLP (S-Nitrosylation of Muscle LIM Protein) Facilitates Myocardial Hypertrophy Through TLR3 (Toll-Like Receptor 3)-Mediated RIP3 (Receptor-Interacting Protein Kinase 3) and NLRP3 (NOD-Like Receptor Pyrin Domain Containing 3) Inflammasome Activation. Circulation 141(12): 984-1000.
2.Xin Tang#, Shuang Zhao#, Jieqiong Liu#, Xiameng Liu, Xinqi Sha, Changgao Huang, Lulu Hu, Shixiu Sun, Yuanqing Gao, Hongshan Chen, Zhiren Zhang, Dongjin Wang, Yuexi Gu, Shaoliang Chen, Liansheng Wang, Aihua Gu, Feng Chen, Jun Pu, Xin Chen, Bo Yu, Liping Xie, Zhengrong Huang, Yi Han*, Yong Ji* (2023). Mitochondrial GSNOR Alleviates Cardiac Dysfunction via ANT1 Denitrosylation. Circ Res 133(3): 220-236.
3.Shanshan Luo#, Chuiyu Kong#, Shuang Zhao#, Xin Tang#, Yu Wang, Xuechun Zhou, Rui Li, Xingeng Liu, Xinlong Tang, Shixiu Sun, Wei Xie, Zhi-Ren Zhang, Qing Jing, Aihua Gu, Feng Chen, Dongjin Wang, Hong Wang*, Yi Han*, Liping Xie*, Yong Ji* (2023). Endothelial HDAC1-ZEB2-NuRD Complex Drives Aortic Aneurysm and Dissection Through Regulation of Protein S-Sulfhydration. Circulation 147(18): 1382-1403.
4.Shuang Zhao#, Xin Tang#, Zian Miao, Yurong Chen, Jiawei Cao, Tianyu Song, Daiting You, Yanqing Zhong, Zhe Lin, Dan Wang, Zhiguang Shi, Xinlong Tang, Dongjin Wang, Shaoliang Chen, Liansheng Wang, Aihua Gu, Feng Chen, Liping Xie, Zhengrong Huang*, Hong Wang*, Yong Ji* (2022). Hsp90 S-nitrosylation at Cys521, as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis. Redox Biol 52: 102290.
5.Xin Tang#, Jiaxin Tian, Liping Xie, Yong Ji* (2019). γ-catenin alleviates cardiac fibrosis through inhibiting phosphorylation of GSK-3β. J Biomed Res 0(0): 1-9.
6.Meng-Lin Chao#, Shanshan Luo#, Chao Zhang, Xuechun Zhou, Miao Zhou, Junyan Wang, Chuiyu Kong, Jiyu Chen, Zhe Lin, Xin Tang, Shixiu Sun, Xinlong Tang, Hongshan Chen, Hong Wang, Dongjin Wang, Jin-Peng Sun, Yi Han*, Liping Xie*, Yong Ji* (2021). S-nitrosylation-mediated coupling of G-protein alpha-2 with CXCR5 induces Hippo/YAP-dependent diabetes-accelerated atherosclerosis. Nat Commun 12(1): 4452.
7.Lihong Pan#, Zhe Lin#, Xin Tang, Jiaxin Tian, Qiao Zheng, Jin Jing, Liping Xie, Hongshan Chen, Qiulun Lu, Hong Wang, Qingguo Li*, Yi Han*, Yong Ji* (2020). S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction. Arterioscler Thromb Vasc Biol 40(1): 175-188.
8.Liping Xie#, Haihua Feng, Sha Li, Guoliang Meng, Shangmin Liu, Xin Tang, Yan Ma, Yi Han, Yujiao Xiao, Yue Gu, Yongfeng Shao, Chung-Min Park, Ming Xian, Yu Huang, Albert Ferro, Rui Wang, Philip K Moore, Hong Wang*, Yong Ji* (2016). SIRT3 Mediates the Antioxidant Effect of Hydrogen Sulfide in Endothelial Cells. Antioxid Redox Signal 24(6): 329-343.
9.Yue Gu#, Xin Tang, Liping Xie, Guoliang Meng*, Yong Ji* (2016). Aliskiren improves endothelium-dependent relaxation of thoracic aorta by activating PI3K/Akt/eNOS signal pathway in SHR. Clin Exp Pharmacol Physiol 43(4): 450-458.
10.Guoliang Meng#, Yujiao Xiao, Yan Ma, Xin Tang, Liping Xie, Jieqiong Liu, Yue Gu, Ying Yu, Chung-Min Park, Ming Xian, Xin Wang, Albert Ferro, Rui Wang, Philip K Moore, Zhiren Zhang, Hong Wang, Yi Han*, Yong Ji* (2016). Hydrogen Sulfide Regulates Krüppel-Like Factor 5 Transcription Activity via Specificity Protein 1 S-Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy. J Am Heart Assoc 5(9).
11.Guoliang Meng#, Jinbiao Zhu, Yujiao Xiao, Zhengrong Huang, Yuqing Zhang, Xin Tang, Liping Xie, Yu Chen, Yongfeng Shao, Albert Ferro, Rui Wang, Philip K Moore, Yong Ji* (2015). Hydrogen Sulfide Donor GYY4137 Protects against Myocardial Fibrosis. Oxid Med Cell Longev 2015: 691070.
12.Xuesong Li#, Ruigong Zhu#, Hong Jiang#, Quanwen Yin, Jiaming Gu, Jiajing Chen, Xian Ji, Xuan Wu, Haiping Fu, Hui Wang, Xin Tang, Yuanqing Gao, Bingjian Wang*, Yong Ji*, Hongshan Chen* (2022). Autophagy enhanced by curcumin ameliorates inflammation in atherogenesis via the TFEB-P300-BRD4 axis. Acta Pharm Sin B 12(5): 2280-2299.
13.Xuesong Li#, Xiang Chen#, Longbin Zheng#, Minghong Chen, Yunjia Zhang, Ruigong Zhu, Jiajing Chen, Jiaming Gu, Quanwen Yin, Hong Jiang, Xuan Wu, Xian Ji, Xin Tang, Mengdie Dong, Qingguo Li*, Yuanqing Gao*, Hongshan Chen* (2023). Non-canonical STING-PERK pathway dependent epigenetic regulation of vascular endothelial dysfunction via integrating IRF3 and NF-κB in inflammatory response. Acta Pharm Sin B 13(12): 4765-4784.
14.Hui Wang#, Haiping Fu#, Ruigong Zhu#, Xuan Wu, Xian Ji, Xuesong Li, Hong Jiang, Zhe Lin, Xin Tang, Shixiu Sun, Jiajing Chen, Xin Wang, Qingguo Li, Yong Ji, Hongshan Chen* (2020). BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. Aging (Albany NY) 12(10): 9240-9259.
15.Pengping Li#, Wei Wu#, Tingting Zhang#, Ziyu Wang#, Jie Li, Mengyan Zhu, Yuan Liang, Wenhua You, Kening Li, Rong Ding, Bin Huang, Lingxiang Wu, Weiwei Duan, Yi Han, Xuesong Li, Xin Tang, Xin Wang, Han Shen, Qianghu Wang, Hong Yan*, Xinyi Xia*, Yong Ji*, Hongshan Chen* (2021). Implications of cardiac markers in risk-stratification and management for COVID-19 patients. Crit Care 25(1): 158.
16.Ruigong Zhu#, Xian Ji, Xuan Wu, Jiajing Chen, Xuesong Li, Hong Jiang, Haiping Fu, Hui Wang, Zhe Lin, Xin Tang, Shixiu Sun, Qingguo Li*, Bingjian Wang*, Hongshan Chen* (2022). Melatonin antagonizes ovarian aging via YTHDF2-MAPK-NF-κB pathway. Genes Dis 9(2): 494-509.
