范君婷,博士,南京医科大学,药学院,副教授。
研究方向:
中药与微生物药学中活性成分的分离分析、生物合成及药效作用机制研究,主要集中于活性环肽类成分研究。
联系方式:
juntingfan@njmu.edu.cn
教育经历:
2005.7-2011.1, 中国科学院昆明植物研究所,植物化学与西部植物资源
持续利用国家重点实验室,天然药物化学,博士。
2001.9-2005.6, 中国药科大学,中药学院,中药学,学士。
工作经历:
2020.9-至今, 南京医科大学,药学院,副教授
2019.2-2020.2,美国辛辛那提大学University of Cincinnati,药学院,访问学者
2011.8-2020.8,南京医科大学,药学院,讲师
2011.2-2011.4,中国科学院昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,研究实习员
主要科研课题:
1. 国家自然科学基金青年项目,31500278,2016/01-2018/12,主持。
2. 江苏省卫生计生委医学科研课题,Z2018035,2018/11-2023/12主持。
3. 江苏省高校自然科学研究项目,13KJB360002,2013/08-2015/12,主持。
4. 南京医科大学科技发展基金,2011NJMU172,主持。
主要学术论文:
1. Yali Du, Yuan Xia, Lingrui Wu, Lu Chen, Jiale Rong, Junting Fan*, Yijun Chen*, Xuri Wu*. Selective biosynthesis of a rhamnosyl nosiheptide by a novel bacterial rhamnosyltransferase. Microbial Biotechnology, 2024, 17(1): 1-12.
2. Xiaoya Xu, Nan Jiang, Shangming Liu, Yang Jin, Yuhan Cheng, Tong Xu, Xin Wang, Yuanhua Liu, Mingwan Zhang, Shuhu Du, Junting Fan*, Aixia Zhang*. Moroidin, a cyclopeptide from the seeds of Celosia cristata that induces apoptosis in A549 human lung cancer cells. Journal of Natural Products, 2022, 85(8): 1918-1927.
3. Weiwei Wang#, Junting Fan#, Guang Zhu, Jing Wang, Yumei Qian, Hongxia Li, Jianming Ju, Lingling Shan. Targeted Prodrug-based Self-assembled Nanoparticles for Cancer Therapy. International Journal of Nanomedicine, 2020, 15: 2921-2933.
4. Tianyong Hu, Jianming Ju; Lihua Mo, Li Ma, Wenhui Hu, Rongrong You, Xueqing Chen, Yanyan Chen, Zhiqiang Liu, Shuqi Qiu, Junting Fan*, Baohui Cheng*. Anti-inflammation action of xanthones from Swertia chirayita by regulating COX-2/NF-kappa B/MAPKs/Akt signaling pathways in RAW 264.7 macrophage cells. Phytomedicine, 2019, 55: 214-221.
5. Liu Li#, Yi Ji#, Junting Fan#, Furong Li, Yan Li, Mianhua Wu*, Haibo Cheng*, Changliang Xu*. Demethylzeylasteral (T-96) inhibits triple-negative breast cancer invasion by blocking the canonical and non-canonical TGF-β signaling pathways. Naunyn-Schmiedebergs Archives of Pharmacology, 2019, 392(5): 593-603.
6. Lingyu Ruan#, Junting Fan#, Wei Hong, He Zhao, Minghui Li, Lei Jiang, Yonghong Fu, Yuexiao Xing, Cheng Chen, Junsong Wang*. Isoniazid-induced hepatotoxicity and neurotoxicity in rats investigated by 1H NMR based metabolomics approach. Toxicology Letters, 2018, 295: 256-269.
7. Jun-Ting Fan#, Yun-hao Dai, Hong-xue Shen, Jian-ming Ju*, Zhi-Ying Zhao*. Application of soluplus to improve the flowability and dissolution of baicalein phospholipid complex. Molecules, 2017, 22: 776-786.
8. Yang Jin#, Junting Fan#, Xiaoling Gu, Liying Zhang, Jing Han, Shuhu Du, Aixia Zhang. Neuroprotective activity of cerebrosides from Typhonium giganteum by regulating caspase-3 and Bax/Bcl-2 signaling pathways in PC12 cells. Journal of Natural Products, 2017, 80(6): 1734-1741.
9. Xianguo Ren#, Yun Bo#, Junting Fan#, Maosheng Chen#, Daliang Xu, Yangdong, Haowei He, Xianzhi Ren, Rong Qu, Yulian Jin, Weihong Zhao*, Changliang Xu*. Dalbergioidin ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. Mediators of inflammation, 2016: ID 5147571.
主要发明专利:
1. 张爱霞, 范君婷,徐筱雅,刘尚明,金阳,蒋南,都述虎. 鸡冠花子中荨麻科类型环肽的制备方法及其在抗肿瘤药物中的应用. 2023-09-08, CN202210162753.7.