范君婷

发布时间:2021-06-18浏览次数:2113

范君婷,博士,南京医科大学,药学院,副教授。

 

研究方向:

中药与微生物药学中活性成分的分离分析、生物合成及药效作用机制研究,主要集中于活性环肽类成分研究。

 

联系方式:

juntingfan@njmu.edu.cn

 

教育经历:

2005.7-2011.1,   中国科学院昆明植物研究所植物化学与西部植物资源

   持续利用国家重点实验室,天然药物化学,博士。

2001.9-2005.6,   中国药科大学中药学院,中药学,学士

 

工作经历:

2020.9-至今,  南京医科大学,药学院,副教授

2019.2-2020.2美国辛辛那提大学University of Cincinnati,药学院,访问学者

2011.8-2020.8南京医科大学,药学院,讲师

2011.2-2011.4中国科学院昆明植物研究所,植物化学与西部植物资源持续利用国家重点实验室,研究实习员

 

主要科研课题:

1. 国家自然科学基金青年项目315002782016/01-2018/12主持

2. 江苏省卫生计生委医学科研课题,Z20180352018/11-2023/12主持。

3. 江苏省高校自然科学研究项目13KJB3600022013/08-2015/12主持

4. 南京医科大学科技发展基金,2011NJMU172主持。

 

主要学术论文:

1. Yali Du, Yuan Xia, Lingrui Wu, Lu Chen, Jiale Rong, Junting Fan*, Yijun Chen*, Xuri Wu*. Selective biosynthesis of a rhamnosyl nosiheptide by a novel bacterial rhamnosyltransferase. Microbial Biotechnology, 2024, 17(1): 1-12.

2. Xiaoya Xu, Nan Jiang, Shangming Liu, Yang Jin, Yuhan Cheng, Tong Xu, Xin Wang, Yuanhua Liu, Mingwan Zhang, Shuhu Du, Junting Fan*, Aixia Zhang*. Moroidin, a cyclopeptide from the seeds of Celosia cristata that induces apoptosis in A549 human lung cancer cells. Journal of Natural Products, 2022, 85(8): 1918-1927.

3. Weiwei Wang#, Junting Fan#, Guang Zhu, Jing Wang, Yumei Qian, Hongxia Li, Jianming Ju, Lingling Shan. Targeted Prodrug-based Self-assembled Nanoparticles for Cancer Therapy. International Journal of Nanomedicine, 2020, 15: 2921-2933.

4. Tianyong Hu, Jianming Ju; Lihua Mo, Li Ma, Wenhui Hu, Rongrong You, Xueqing Chen, Yanyan Chen, Zhiqiang Liu, Shuqi Qiu, Junting Fan*, Baohui Cheng*. Anti-inflammation action of xanthones from Swertia chirayita by regulating COX-2/NF-kappa B/MAPKs/Akt signaling pathways in RAW 264.7 macrophage cells. Phytomedicine, 2019, 55: 214-221.

5. Liu Li#, Yi Ji#, Junting Fan#, Furong Li, Yan Li, Mianhua Wu*, Haibo Cheng*, Changliang Xu*. Demethylzeylasteral (T-96) inhibits triple-negative breast cancer invasion by blocking the canonical and non-canonical TGF-β signaling pathways. Naunyn-Schmiedebergs Archives of Pharmacology, 2019, 392(5): 593-603.

6. Lingyu Ruan#, Junting Fan#, Wei Hong, He Zhao, Minghui Li, Lei Jiang, Yonghong Fu, Yuexiao Xing, Cheng Chen, Junsong Wang*. Isoniazid-induced hepatotoxicity and neurotoxicity in rats investigated by 1H NMR based metabolomics approach. Toxicology Letters, 2018, 295: 256-269.

7. Jun-Ting Fan#, Yun-hao Dai, Hong-xue Shen, Jian-ming Ju*, Zhi-Ying Zhao*. Application of soluplus to improve the flowability and dissolution of baicalein phospholipid complex. Molecules, 2017, 22: 776-786.

8. Yang Jin#, Junting Fan#, Xiaoling Gu, Liying Zhang, Jing Han, Shuhu Du, Aixia Zhang. Neuroprotective activity of cerebrosides from Typhonium giganteum by regulating caspase-3 and Bax/Bcl-2 signaling pathways in PC12 cells. Journal of Natural Products, 2017, 80(6): 1734-1741.

9. Xianguo Ren#, Yun Bo#, Junting Fan#, Maosheng Chen#, Daliang Xu, Yangdong, Haowei He, Xianzhi Ren, Rong Qu, Yulian Jin, Weihong Zhao*, Changliang Xu*. Dalbergioidin ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. Mediators of inflammation, 2016: ID 5147571.

 

主要发明专利:

1. 张爱霞, 范君婷,徐筱雅,刘尚明,金阳,蒋南,都述虎. 鸡冠花子中荨麻科类型环肽的制备方法及其在抗肿瘤药物中的应用. 2023-09-08, CN202210162753.7.