陈立娜

发布时间:2020-07-01浏览次数:10

陈立娜,女,南京医科大学教授,博士生导师。国家自然科学基金网评专家,获江苏中医药科学技术奖二等奖(排名第二),江苏省高校“青蓝工程”优秀青年骨干教师培养人选,南京医科大学优秀中青年学科(学术)带头人、 “十二五”科技工作先进个人、“优秀研究生导师团队”成员。主持多项国家级、省级科研课题。在国内外主要期刊发表研究论文50余篇。以第一作者身份获授权国家发明专利7件,主编或参编“十二五”、“十三五”教材7部。

目前研究方向:现代分析技术在天然药物活性成分研究中的应用;天然药物活性成分及其质量评价研究。

招生方向:现代药物分析

近期发表的SCI论文

1. Chenghong Sun, Linli Pan, Lei Zhang, Jiaojiao Huang,Dandan Yao,Chong-Zhi Wang,Yu Zhang, Nan Jiang, Lina Chen*,Chun-Su Yuan.A biomimetic fluorescent nanosensor based on imprinted polymers modified with carbon dots for sensitive detection of alpha-fetoprotein in clinical samples, analyst, 2019,144:6760-6772.

2. Jiaojiao Huang, Chenghong Sun,Dandan Yao, Chong-Zhi Wang,Lei Zhang,Yu Zhang, Lina Chen*,Chun-Su Yuan. Novel surface imprinted magnetic mesoporous silica as artificial antibodies for efficient discovery and capture of candidate nNOS–PSD-95 uncouplers for stroke treatment, Journal of Materials Chemistry B,2018,6,1531-1542.

3. Dandan Yao, Lei Zhang, Jiaojiao Huang, Chenghong Sun, Yu Zhang, Xiaoli Gu, Chong-Zhi Wang, Fei Li, Lina Chen*, Chun-Su Yuan. A surface magnetic imprinted polymers as artificial receptors for selective and efficient capturing of new neuronal nitric oxidesynthase–post synaptic density protein-95 uncouplers, Journal of Pharmaceutical and Biomedical Analysis ,2018,154:180–190.

4. Xiaoli Gu,Jiaojiao Huang,Lei Zhang,Yu zhang, Chong-Zhi Wang, Chenghong Sun, Dandan Yao,Fei Li, Lina Chen* ,Chun-Su Yuan. Efficient discovery and capture of new neuronal nitric oxide synthase-postsynaptic density protein-95 uncouplers from herbal medicines using magnetic molecularly imprinted polymers as artificial antibodies. Journal of Separation Science, 2017,40(17):3522-3534.

5. Chenghong Sun, Jinhua Wang, Jiaojiao Huang, Dandan Yao, Chong-Zhi Wang, Lei Zhang, Shuying Hou*, Lina Chen* ,Chun-Su Yuan. The multi-template molecularly imprinted polymer based on SBA-15 for selective separation and determination of Panax notoginseng Saponins simultaneously in biological samples. Polymers,2017,9(12):653.

6. Hongliang He, Xiaoli Gu, Liying Shi, Junli Hong, Hongjuan Zhang, Yankun Gao, Shuhu Du, Lina Chen*. Molecularly imprinted polymers based on SBA-15 for selective solid-phase extraction of baicalein from plasma samples. Analytical and Bioanalytical Chemistry, 2015,407(2):509–519.

7. Hongliang He, Hong Li, Yankun Gao, Dong Chen, Liying Shi, Jin Peng, Shuhu Du, Lina Chen*. A novel molecularly imprinted polymer for the solid-phase extraction of Tanshinones from serum, Analytical Letters, 2015, 48:47-60.

8. Shuying Hou, Songling Yang, Hongliang He, Yan Chen, Jinhua Wang, Yang Wang*, Lina Chen*. Multi-templates molecularly imprinted polymer for the specific solid-phase extraction of saponins from Panax notoginseng herbal extract. Current Pharmaceutical Analysis, 2015,11(3):292-299.

9. Xiaoli Gu, Hongliang He, Chong-zhi Wang, Yankun Gao, Hongjuan Zhang, Junli Hong,ShuhuDu,LinaChen*,Chun-suYuan.Synthesis of surface nano-molecularly imprinted polymers for sensitive baicalin detection from biological samples. RSC Advances, 2015, 5, 41377–41384.

10. Hong Li, Hongliang He, Jiaojiao Huang, Chong-Zhi Wang, Xiaoli Gu, Yankun Gao, Hongjuan Zhang, Shuhu Du, Lina Chen*, Chun-Su Yuan. A novel molecularly imprinted method with computational simulation for the affinity isolation and knockout of baicalein from Scutellaria baicalensis. Biomedical Chromatography, 2016,30(2):117-125.

代表性发明专利

1.陈立娜,黄姣姣,孙成红,姚丹丹,张宇,张爱霞. 一种基于磁性介孔分子筛的nNOS-PSD-95解偶联剂表面印记聚合物的制备方法,ZL201710474123.2

2.陈立娜,姚丹丹,顾小丽,黄姣姣,孙成红,张宇. 一种磁性人工受体及其制备方法和应用,ZL201710474093.5

3.陈立娜,孙成红,黄姣姣,姚丹丹,顾小丽,魏芳弟. 一种荧光纳米分子印记仿生传感器及其制备方法和应用,ZL201710592816.1

4. 陈立娜,李虹,何宏亮,高艳坤,史丽英,都述虎. 黄芩素分子印迹聚合物及其制备方法和应用,ZL201310408025.0

5. 陈立娜,何宏亮,高艳坤. 多模板单分散三七活性皂苷分子印迹聚合物及其制备方法,ZL201310495697.X

6. 陈立娜,何宏亮,史丽英,程清清,高艳坤,都述虎. 介孔分子筛SBA-15复合纳米表面印迹聚合物及其制备方法,ZL201310496400.1

7. 陈立娜,都述虎,贾宪军,刘利萍. 丹参酮类化合物芯-壳结构复合纳米表面分子印记聚合物的制备方法,ZL201010167614.0


代表性教材

1.生药学与天然药物化学实验,化学工业出版社,主编,20193

2.药用植物学,华中科技大学出版社,主编,20207

3.生药学,华中科技大学出版社,副主编,202012

4.生药学(第四版),中国医药科技出版社,编委,20201

5.药用植物学与生药学(第二版),人民卫生出版社,副主编,201310


联系方式:Emailchenlina@njmu.edu.cn