报告题目1：Reversal of Multidrug Resistance by Tyrosine Kinase Inhibitors in Cancer
报告人：陈哲生教授美国St. John’s大学药学系
报告题目2：Biomarker research: from basic science to clinical application
报告人：杨冬华教授美国Fox Chase癌症中心
报告时间：5月17日（周六）下午2：30
报告地点：药学院310室
代表作
陈哲生教授
1）Kathawala, R.J., Sodani, K., Chen, K., Patel, A., Abuznait, A.H., Anreddy, N., Sun, Y.L., Kaddoumi, A., Ashby Jr. C.R., and Chen, Z.S. Masitinib antagonizes ATP-binding cassette subfamily C member 10-mediated paclitaxel resistance: A priclinical study. Molecular CancerTherapeutics, in press, 2014
２） Chen, G., Chen, R., Zou, C., Yang, D. and Chen, Z. S. Fragmented polymer nanotubes fromsonication-inducedscission with thermo-responsive gating system for anti-cancer drug delivery. Journal of Materials Chemistry B. 2:1327-1334, 2014
３） Sen, R., Natarajan,K., Bhullar,J., Shukla, S., Fang,H. B., Cai, L., Chen, Z.S., Ambudkar, S. V.and Baer, M. R. The novel BCR-ABL and FLT3 inhibitor ponatinib is a potent inhibitor of themultidrug resistance-associated ATP-binding cassette transporter ABCG2, Mol Cancer Thera, 2012.
杨冬华教授
1) Yang DH, McKee KK, Chen ZL, Mernaugh G, Strickland S, Zent R and Yurchenco PD. Renal collecting system growth andfunction depend upon embryonic gamma1 laminin expresseion. Development. 2011 Oct;138(20):4535-44. Epub 2011 Sep 8.
2) Yang D-H, Cai KQ, Roland IH, Smith ER and Xu XX Disabled-2 is an epithelial surface positioning gene. J BiolChem. 2007 Apr 27;282(17):13114-22.
3) Yang D-H, Z Fazili, E.R. Smith, , Q Cai, A. Klein-Szanto, C. Cohen, IR Horowitz and X.X.Xu Disabled-2heterozygous mice are predisposed to endometrial and ovarian tumorigenesis and exhibit sex-biased embryoniclethality in a p53 null background. Am. J. Path. 2006, 169:258-267.
