唐欣

发布时间:2021-06-24浏览次数:1858


唐欣,南京医科大学药学院,江苏省心脑血管药物重点实验室,副教授。2016年获得南京医科大学,病理学与病理生理学,硕士学位;2019年获得南京医科大学,病理学与病理生理学,博士学位;2019年至今,在南京医科大学药学院任教。

 

研究方向:心血管重构相关心血管疾病的病理生理分子机制及药物防治研究。

科研项目及获奖:参与国家自然科学基金重大研究计划重点项目、面上项目和青年项目等4项。主持国家自然科学基金青年基金项目1项,江苏省科技厅青年基金项目1南京医科大学发展基金项目 1 项。获得中华医学会科技奖一项,获得国家专利一项。Email: njmutangxin@njmu.edu.cn

 

近期发表的论文:

1.    Tang X, Pan L, Zhao S, Dai F, Chao M, Jiang H, Li X, Lin Z, Huang Z, Meng G, Wang C, Chen C, Liu J, Wang X, Ferro A, Wang H, Chen H, Gao Y, Lu Q, Xie L, Han Y and Ji Y. S-Nitrosylation of Muscle LIM Protein Facilitates Myocardial Hypertrophy Through Toll-Like Receptor 3-Mediated Receptor-Interacting Protein Kinase 3 and NLRP3 Inflammasome Activation. Circulation. 2020. doi: 10.1161/CIRCULATIONAHA.119.042336.

2.    Tang X, Tian J, Xie L and Ji Y. gamma-catenin alleviates cardiac fibrosis through inhibiting phosphorylation of GSK-3beta. J Biomed Res. 2019;0:1-9. doi: 10.7555/JBR.33.20190070.

3.    Pan L, Lin Z, Tang X, Tian J, Zheng Q, Jing J, Xie L, Chen H, Lu Q, Wang H, Li Q, Han Y and Ji Y. S-Nitrosylation of Plastin-3 Exacerbates Thoracic Aortic Dissection Formation via Endothelial Barrier Dysfunction. ArteriosclerThrombVasc Biol.2020;40:175-188. doi: 10.1161/ATVBAHA.119.313440.

4.    Gu Y, Tang X, Xie L, Meng G and Ji Y. Aliskiren improves endothelium-dependent relaxation of thoracic aorta by activating PI3K/Akt/eNOS signal pathway in SHR. Clin Exp Pharmacol Physiol. 2016;43:450-8. doi: 10.1111/1440-1681.12550.

5.    Meng G, Xiao Y, Ma Y, Tang X, Xie L, Liu J, Gu Y, Yu Y, Park CM, Xian M, Wang X, Ferro A, Wang R, Moore PK, Zhang Z, Wang H, Han Y and Ji Y. Hydrogen Sulfide Regulates Kruppel-Like Factor 5 Transcription Activity via Specificity Protein 1 S-Sulfhydration at Cys664 to Prevent Myocardial Hypertrophy. J Am Heart Assoc. 2016;5. doi: 10.1161/JAHA.116.004160.

6.    Xie L, Feng H, Li S, Meng G, Liu S, Tang X, Ma Y, Han Y, Xiao Y, Gu Y, Shao Y, Park CM, Xian M, Huang Y, Ferro A, Wang R, Moore PK, Wang H and Ji Y. SIRT3 Mediates the Antioxidant Effect of Hydrogen Sulfide in Endothelial Cells. Antioxid Redox Signal. 2016;24:329-43. doi: 10.1089/ars.2015.6331.

7.    Meng G, Zhu J, Xiao Y, Huang Z, Zhang Y, Tang X, Xie L, Chen Y, Shao Y, Ferro A, Wang R, Moore PK and Ji Y. Hydrogen Sulfide Donor GYY4137 Protects against Myocardial Fibrosis. Oxid Med Cell Longev. 2015;2015:691070. doi: 10.1155/2015/691070.

8.    Wang H, Fu H, Zhu R, Wu X, Ji X, Li X, Jiang H, Lin Z, Tang X, Sun S, Chen J, Wang X, Li Q, Ji Y and Chen H. BRD4 contributes to LPS-induced macrophage senescence and promotes progression of atherosclerosis-associated lipid uptake. Aging (Albany NY).2020;12:9240-9259.doi: 10.18632/aging.103200

9.    Li P, Wu W, Zhang T, Wang Z, Li J, Zhu M, Liang Y, You W, Li K, Ding R, Huang B, Wu L, Duan W, Han Y, Li X, Tang X, Wang X, Shen H, Wang Q, Yan H, Xia X, Ji Y and Chen H. Implications of cardiac markers in risk-stratification and management for COVID-19 patients.Crit Care.2021;25:158.doi: 10.1186/s13054-021-03555-z